杨芳

教授简介：

Ph. D, Associate Professor, Doctoral supervisor

State Key Laboratory of Bioelectronics

Jiangsu Key Laboratory for Biomaterials and Devices

School of Biological Science & Medical Engineering

SoutheastUniversity

Nanjing, Jiangsu, P. R. China 210096

Tel: 86-25-83272476-8009

Fax: 86-25-83272460

Email: yangfang2080@seu.edu.cn

研究方向：

Research Interestes:

• Fabrication novel microbubbles for multimodality biomedical imaging 
• Ultrasound imaging guided drug delivery
• Novel ultrasound sensitive micro-, nano- delivery system
• Ultrasonic theranostics

研究成果：

Fundings:

• National Natural Science Foundation of China(31000453,31370019)
•  
• National Key Basic Research Program of China (2013CB733804)
•  
• Author of National Excellent Doctoral Dissertation of PR China (201259)
•  
• Specialized Research Fund for the Doctoral Program of Higher Education of China (20100092120038)

Selected Publications:

[1] Fang Yang, Xiaoxian Zhang, Lina Song, Huating Cui, John N. Myers, Tingting Bai, Ying Zhou, Zhan Chen, Ning Gu. Controlled Drug Release and Hydrolysis Mechanism of Polymer–Magnetic Nanoparticle Composite. ACS Appl. Mater. Interfaces, 2015, 7 (18): 9410-9419.

[2] Lei Duan, Fang Yang, Lina Song, Kun Fang, Jilai Tian, Yijun Liang, Mingxi Li, Ning Xu, Zhongda Chen, Yu Zhang, Ning Gu. Controlled assembly of magnetic nanoparticles on microbubbles for multimodal imaging. Soft Matter, 2015, , 11, 5492-5500.

[3] Fangfang Shi, Fang Yang, Xiangfeng He, Ying Zhang, Songyan Wu, Miao Li, Yunxia Zhang, Wu Di, Jun Dou, Ning Gu. Inhibitory effect of epirubicin-loaded lipid microbubbles with conjugated anti-ABCG2 antibody combined with therapeutic ultrasound on multiple myeloma cancer stem cells. J Drug Target, 2015, DOI: 10.3109/1061186X.2015.1052075.

[4] Fang Yang, Mingxi Li, Huating Cui, Tuantuan Wang, Zhongwen Chen, Lina Song, Zhuxiao Gu, Yu Zhang, Ning Gu. Altering the response of intracellular reactive oxygen to magnetic nanoparticles using ultrasound and microbubbles. SCIENCE CHINA Materials, 2015, 58(6): 467-480.

[5] Kun Fang, Fang Yang, Qiying Zhang, Tianzhu Zhang, Ning Gu, Fabrication of nonporous and porous cationic PLGA microspheres, Materials Letters, 2014, 117(15): 86-89. 

[6] Fang Yang, Qing Wang, Zhuxiao Gu, Kun Fang, Gerard Marriott, Ning Gu. Silver nanoparticle-embedded micro-bubble as a dual-mode ultrasound and optical imaging probe. ACS Appl. Mater. Interfaces, 2013, 5 (18): 9217–9223. 

[7] Jiayi Tong, Jiandong Ding, Xiangbo Shen, Long Chen, Yeping Bian, Genshan Ma, Yuyu Yao, Fang Yang*. Mesenchymal Stem Cell Transplantation Enhancement in Myocardial Infarction Rat Model under Ultrasound Combined with Nitric Oxide Microbubbles. PLoS ONE 2013, 8(11): e80186.

[8] Chao Wang, Fang Yang, Zhihong Xu, Dongquan Shi, Dongyang Chen, Jin Dai, Ning Gu, Qing Jiang. Intravenous release of NO from lipidic microbubbles accelerates deep vein thrombosis resolution in a rat model. Thromb Res (2013), 131（1）：e31-e38.

[9] Fang Yang, Sunling Hu, Yu Zhang, Xiaowei Cai, Yan Huang, Feng Wang, Song Wen, Gaojun Teng, Ning Gu. A Hydrogen Peroxide-Responsive O2 Nanogenerator for Ultrasound and Magnetic-Resonance Dual Modality Imaging. Adv. Mater. 2012, 24(38): 5205–5211.

[10] Xiaowei Cai, Fang Yang, Ning Gu. Applications of Magnetic Microbubbles for Theranostics. Theranostics, 2012; 2(1):103-112. 

[11] Wen He, Fang Yang, Yihang Wu, Song Wen, Ping Chen, Yu Zhang, Ning Gu. Microbubbles with surface coated by superparamagnetic iron oxide nanoparticles. Materials Letters, 2012, 68(1): 64-67.

[12] Fang Yang, Miao Zhang, Wen He, Ping Chen, Xiaowei Cai, Li Yang, Ning Gu and Junru Wu. Controlled Release of Fe3O4 Nanoparticles in Encapsulated Microbubbles to Tumor Cells via Sonoporation and Associated Cellular Bioeffects, Small 2011, 7(7), 902–910

[13] Fang Yang, Ping Chen, Wen He, Ning Gu, Xizhi Zhang, Kun Fang, Yu Zhang, JianFei Sun, Jiayi Tong. Bubble Microreactors Triggered by an Alternating Magnetic Field as Diagnostic and Therapeutic Delivery Devices. Small, 2010, 6(12): 1300-1305.

[14] Fang Yang, Yixin Li, Zhongpin Chen, Yu Zhang, Junru Wu, Ning Gu. Superparamagnetic Iron Oxide Nanoparticle-embedded Encapsulated Microbubbles as Dual Magnetic Resonance and Ultrasound Imaging Contrast Agents. Biomaterials, 2009, 30(23-24):3 882-3890.

[15] Fang Yang, Ning Gu, Di Chen, Xiaoyu Xi, Dong Zhang, Yixin Li, Junru Wu. Experimental study on cell self-sealing during sonoporation. Journal of Controlled Release, 2008, 131(3): 205-210.

[16] Fang Yang, Ling Li, Yixin Li, Zhongping Chen, Junru Wu, Ning Gu. Superparamagnetic nanoparticle-inclusion microbubbles for ultrasound contrast agents. Phys. Med. Biol, 2008, 53(21): 6129-6141.

[17] Fang Yang, Aiyuan Gu, Zhongping Chen, Ning Gu, Min Ji. Multiple emulsion microbubbles for ultrasound imaging. Materials Letters, 2008, 62(1): 121-124.

[18] Xiaoyu Xi, Fang Yang, Di Chen, Yi Luo, Dong Zhang, Ning Gu, Junru Wu. A targeting drug-delivery model via interactions among cells and liposomes under ultrasonic excitation. Phys. Med. Biol, 2008(53): 3251-3265.

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